GLB1 (chromosome 23) was observed in the flanking region of an outlier in the test across all four breeds as well as in two pairwise tests (Buhund–Norrbottenspets; Icelandic Sheepdog–Norrbottenspets); mutations in this gene have been linked to metabolic diseases and hypermobile joints [31]. Here, GLB1 is linked to Other metabolic disease.