Our observation that 24 h of incubation with 6-OHDA inhibits autophagy in PC12 cells is consistent with In et al.’s study.9 Recent studies have reported that SNCA is a crucial factor in PD pathogenesis,33, 35, 36, 37 and it is usually recognized as a hallmark of PD. The gene discussed is SNCA; the disease is Parkinson disease.