Matsuo et al.38 demonstrated that MOLM-14, along with FLT3-ITD, carries a series of genotypic aberrancies, such as the insertion ins(11;9) with the fusion hybrid MLL-AF9.38 This complex pattern could justify the partially divergent behavior of MOLM-14 as compared with fresh AML samples. This evidence concerns the gene MLLT3 and acute myeloid leukemia.