Previous studies reported that Lin28A is a direct target of miR-128,28 a microRNA involved in hematopoiesis.29, 30 Different studies have associated miR-128a with leukemia, showing that miR-128a belongs to a set of miRNAs with stringent specificity for AML or ALL.31, 32, 33 Moreover, miR-128a expression was found to be associated with a subgroup of AML patients with high-risk molecular features, refractoriness, relapse and death.31, 33. This evidence concerns the gene LIN28A and acute myeloid leukemia.