GJB2 and keratoderma hereditarium mutilans: Fortunately, five mouse models feature GJB2 modifications have helped elucidate the pathogenesis of KIDS and Vohwinkel Syndrome,25, 28, 47 and have suggested a role for Cx26 in both epidermal barrier establishment and cutaneous wound healing.30 Our study offers further evidence for the influence of Cx26 during cutaneous wound healing and illustrates a link between Cx26 disorders and aberrant keratinocyte differentiation.