ZEB2 has been implicated in EMT induction, where it acts by directly repressing E-cadherin and indirectly promoting Vimentin expression.24, 25 In a previous study, we also reported a correlation between ZEB2 and EMT markers expression.26 Since it is well-known that EMT is involved in invasion and metastasis of cancer cells, it was tested whether miR-30a-5p levels in ccRCC cells affect the induction of EMT. This evidence concerns the gene CDH1 and nonpapillary renal cell carcinoma.