This mechanism ensures sufficient energy (ATP) to the anabolic processes that support the synthesis of the building blocks for the dividing cells.40 A wide number of nuclear-encoded genes required for mitochondria biogenesis and activity have been identified as Myc targets.41, 42 However, if or how Myc regulates the synthesis of AKAP scaffolds involved in cancer-related mitochondrial activities remained largely unexplored. The gene discussed is AKAP1; the disease is cancer.