Lots of studies revealed that regulation of lncRNAs in translational level is similar to common genes.16, 29, 30 In bladder cancer, Ets-2 and C/EBPα could promote UCA1 expression via binding to UCA1 core promoter.16, 17 To investigate the reason for high UCA1 expression in GC, bioinformatics databases including Jaspar database and starBase were used to screen for potential proto-oncogenic transcription factor. Here, UCA1 is linked to urinary bladder cancer.