It has been reported that miR-125b activates NF-κB pathway by targeting A20,20, 21, 22 and activation of NF-κB signaling confers the advantages of tumor cell proliferation and survival.8 Therefore, we analyzed whether miR-125b regulates NPC cell proliferation and apoptosis by targeting A20. Here, TNFAIP3 is linked to nasopharyngeal carcinoma.