Multivariate analysis demonstrated that the incidence of ILD as an underlining disease [odds ratio (OR) 15; 95% CI 1.01–438.0; p = 0.0488] and serum KL-6 [OR 1.0025; 95% CI 1.000504–1.000667; p = 0.0052] were independently associated with 90-day mortality. Here, MUC1 is linked to interstitial lung disease.