In advanced prostate carcinoma and consistent with the reduction in Tbet+ Th1 cells, we noticed a reduction in CXCL10+CD3+ T cells in TLO (Figure 11C) but unexplainably observed intense CXCL10 staining in the transformed glandular epithelium (Figure 11G). The gene discussed is TBX21; the disease is prostate carcinoma.