Based on previous evidence of the cell surface or extracellular role of Hsp90 in migration of neural and cancer cells (Sidera et al., 2004, 2008), as well as the role of Hop/STI1 in promoting glioblastoma cell migration (Fonseca et al., 2012), we sought to investigate if an extracellular complex composed of Hsp90 and Hop/STI1 could be involved in SVZ neuroblast migratory behavior. The gene discussed is STIP1; the disease is cancer.