However, MAL2 (n = 58, P = 0.55) and TPD52 (n = 58, P = 0.672) protein expressions in lymphnode metastasis tissues (data not shown) and MAL2 expression in liver metastasis tissues (n = 38, P = 0.782; Fig 2A) did not exhibit significant elevation relative to primary carcinoma groups. This evidence concerns the gene TPD52 and carcinoma.