Notably, miR-944 expression significantly correlated with incidence of mutated CTNNB1 (p = 0.019) (Fig 1C), a well-studied proto-oncogene [22], in HCC tumors; and miR-223 expression significantly correlated with presence of residual tumor after treatment (p = 0.037) (Fig 1D) and with univariate patient survival (p = 0.016) (Fig 1E). The gene discussed is CTNNB1; the disease is hepatocellular carcinoma.