Gender difference of BDNF levels in patients with schizophrenia have been reported in the past.[11,21–23] Zhang et al[21] reported that no differences in serum BDNF levels were observed between patients with schizophrenia and BMI matched controls; BDNF levels also negatively correlated with BMI gain in female but not in male patients when gender was considered. Here, BDNF is linked to schizophrenia.