In addition, a recent report from a Phase I clinical study has described significant regression of a recurrent GBM in a patient after intracavitary and intraventricular infusion of chimeric antigen receptor (CAR) T-cells targeting IL13RA2 expressing GBM cells, further highlighting the therapeutic advantage of targeting IL13RA2 expressing tumor cells [10, 11]. Here, IL13RA2 is linked to neoplasm.