ALDH2 and Hypertension: ALDH2 was previously shown to be associated with BP and hypertension [8, 10] The acyl-CoA dehydrogenase family member 10 gene (ACAD10) is located at 12q24.12 (NCBI Gene), is ubiquitously expressed (The Human Protein Atlas), and activates the β-oxidation of fatty acids in mitochondria (NCBI Gene).