BA24 was also assessed as we have recently shown lower levels of the serotonin 2A receptor in that region in subjects with mood disorders.23 Finally, PLCB1 levels were measured in the cortex of homozygous knockout (−/−) mice Chrm1−/−, Chrm2−/−, Chrm4−/− and Chrm5−/− to determine whether changes in levels of cortical muscarinic receptors could drive changes in PLCB1. Here, PLCB1 is linked to mood disorder.