MSN and malaria: Additionally, moesin may be involved in key events leading to the development of malaria pathology independent of its interaction with Plasmodium GPI, since moesin was described to be relevant in immunological synapse formation (Itoh et al., 2002; Parameswaran and Gupta, 2013) and in endothelial permeability (Koss et al., 2006; Yao and Tsirka, 2011).