The ACTH-secreting pituitary adenoma is related to a clinical disorder known as Cushing’s disease (CD), which causes adrenal hypercortisolemia and consequent osteoporosis, muscle atrophy, psychiatric disorders, and, ultimately, death (Castinetti et al., 2012; Sulentic, Morris & Grossman, 2000). Here, POMC is linked to osteoporosis.