Among all the specimens, LincIN exerts positive staining in approximately 72% of the breast tumor tissues (63 out of 88, score ranging from 1–2) while only approximately 29% of the normal tissues show positive LincIN expression (9 out of 31, score 1–2; P < 0.001) (Fig. 2b). This evidence concerns the gene ITGB1-DT and breast neoplasm.