In other diseases-such as progressive supranuclear palsy (PSP), corticobasal degeneration (CBD), argyrophilic grain disease (AGD), globular glial Tauopathy (GGT) and aging-related Tau astrogliopathy (ARTAG)-only isoforms with 4R Tau are found in the filaments [1]. The gene discussed is MAPT; the disease is argyrophilic grain disease.