The AUC (95% CI) of [TIMP-2]•[IGFBP7] four hours after ICU admission was 0.80 (0.68–0.91) for prediction of any AKI stage and 0.83 (0.69–0.96) for prediction of stage 2–3 AKI (Fig. 1). The gene discussed is IGFBP7; the disease is acute kidney injury.