TIMP2 and acute kidney injury: Following surgery, mean (SE) [TIMP-2]•[IGFBP7] values from patients who developed AKI increased to a peak of 1.49 (0.87) at 6 h after ICU admission; while mean (SE) [TIMP-2]•[IGFBP7] values from non-AKI patients decreased to a nadir of 0.19 (0.02) at 24 h after ICU admission (Fig. 2).