Using TARGETSCAN and Pic Tar, a list of predicted Klf4-targeting miRNAs was compiled (S1 Table) with the inclusion criteria that (a) the miRNA was predicted to target Klf4 using both the algorithms; (b)it was perfectly conserved in humans and in mice and (c) it was downregulated both at 4 and 24 h of infection. This evidence concerns the gene KLF4 and infection.