HNF4A and Large for gestational age: A fetus inheriting the HNF4A mutation from the father has a similar risk of macrosomia and its complications (shoulder dystocia, obstructed birth, etc) to that associated with maternal inheritance (median corrected birth weight 4200 g) 34. In addition, there is a high risk of fetal hypoglycaemia that may be severe and profound (see above).