An integrated proteomics and genomics analyses in soft tissue leiomyosarcomas identified SNAI2/SLUG as a negative regulator of E‐cadherin expression; knockdown of SNAI2 increased E‐cadherin and decreased vimentin expression that was associated with a decrease in proliferation and invasion (Yang et al., 2010). The gene discussed is CDH1; the disease is leiomyosarcoma.