Age (continuous), ApoE genotype (ApoE-ε4 vs non-ApoE-ε4), hypertension, and platelet medication use were associated (p < 0.2) on simple logistic regression analysis with the presence of CMB (Table 2) and were, therefore, included as potential independent variables in the multiple logistic regression analysis for CMB (Table 3). This evidence concerns the gene APOE and hypertensive disorder.