These included genes which are implicated in inflammation and inflammatory responses to cancer (PTX3, IL8, TNFSF10, SERPINB13 and ANKRD1) and those involved in cell adhesion, cell migration and ECM degradation of importance in metastatic cancer (MMP12, MMP1 and ADAM19). The gene discussed is CXCL8; the disease is metastatic malignant neoplasm.