In this study, we genotyped SNPs (FADS1: rs174547, rs174548, rs174550; FADS2: rs174575, rs174576, rs174583, rs498793 and rs2727270) in 820 patients with type 2 diabetes and compared our findings with those reported in HapMap in a healthy population. This evidence concerns the gene FADS2 and type 2 diabetes mellitus.