Higher serum levels of MDA and CRP have been previously reported in obesity and metabolic syndrome [42] and have also linked obesity to alterations in the lipoprotein particles profile as well as to increased lipid peroxidation, during which the MDA is one of the most abundant products formed [43,44,45,46,47]. The gene discussed is CRP; the disease is obesity due to melanocortin 4 receptor deficiency.