2009). The metabolic characteristics of the DBA/2J mice are depicted in Table 1. At the end of the study, diabetic mice showed threefold higher average fasting blood glucose levels, which were not affected by anti‐IL‐1β treatment. However, the diabetes‐associated elevation of serum FetA levels (88 ± 16%, P < 0.001) was significantly attenuated by anti‐IL‐1β antibody 63 ± 5% (P < 0.001; Fig. 5A). Here, IL1B is linked to diabetes mellitus.