IL4R and posterior cortical atrophy: IL-4 acts by binding to a heterodimeric receptor complex, composed of the IL4Rα and the common gamma chain shared by several IL receptors.27 To evaluate IL4Rα expression patterns in benign and malignant prostate tissue, we investigated expression of IL4Rα in a tissue microarray (TMA) containing both malignant and adjacent benign areas from 36 PCa patients (Figure 1a).