Similar results have been observed in PCa xenograft models where IL4Rα is overexpressed in both androgen-dependent and -independent tumours.36 These results added PCa to the group of solid human tumours where IL4Rα is highly expressed, similar to breast, ovarian and colon cancers.37, 38 Interestingly, we found no significant difference in IL4Rα expression between benign and malignant primary basal prostate cells. This evidence concerns the gene IL4R and colonic neoplasm.