In line with the increased frequency of the homozygous CNDP1 (CTG)5 genotype in the groups of patients with a long history of hemodialysis, a significant negative correlation between serum CN-1 activity and log-transformed hemodialysis duration was found in all patients (r = −0.33; P < 0.0001, Figure 4(a)), T2DM patients only (r = −0.034, P = 0.0006, Figure 4(b)), and nondiabetic hemodialysis patients (r = −0,031, P = 0.004, Figure 4(c)). Here, CNDP1 is linked to type 2 diabetes mellitus.