For example, some siRNAs, such as those targeting CDC42SE2, ITGAM, MYO10, unc-13 homolog D (UNC13D) and TLE4, reduced bacterial load significantly at 2 days p.i. but not significantly at day 1, suggesting that these proteins may be not involved in bacterial internalization or early stage of infection. This evidence concerns the gene MYO10 and infection.