TGFB1 and pulmonary fibrosis: Jin et al. (2016) recently showed that HSYA attenuated BLM-induced pulmonary fibrosis in mice. A previous pilot study in our lab showed that HSYA inhibition of TGF-β1-induced MRC-5 cell activation was associated with the Smad and ERK/MAPK signaling pathways (Pan et al., 2016).