SERPINE1 and endothelial dysfunction: Adipokines are involved in glucose metabolism (e.g., adiponectin, leptin, resistin, visfatin, and PAI-1 [5, 6]), inflammation (e.g., resistin and leptin [7]), reducing inflammation (e.g., adiponectin [5, 7]), coagulation (e.g., PAI-1 [6]), endothelial dysfunction (e.g., PAI-1 [8]), and feeding behavior (e.g., leptin [6]).