The mean IgM responses (OD values) in the afebrile controls, the other confirmed infections and the typhoid infections were 0.29, 0.27, and 0.42 (against STY4539), 0.17, 0.18, and 0.25 (against STY1886), and 0.22, 0.21, and 0.35 (against Vi), respectively. Here, CD40LG is linked to infection.