There is also evidence that interruptions can lead to the presentation of new phenotypes as disruptions in the ATTCT repeats in SCA10 are associated with a higher incidence of seizures (Matsuura et al., 2006) and CAG repeats that normally cause SCA2 can lead to parkinsonism when CAA triplets interrupt the CAG expansion (Charles et al., 2007). Here, ATXN10 is linked to Parkinson disease.