Accordingly, Cal27 with lower basal and MG-induced GLO1 expression were more sensitive in a colony-forming assay to the cytotoxic effect at high MG concentrations, which is consistent with the sensitization to exogenous MG of metastatic melanoma and prostate cancer cell lines after silencing of GLO1 expression [14, 31]. Here, GLO1 is linked to prostate carcinoma.