HDAC4 expression was up-regulated in HSC-T6 cells following TGF-β or PDGF stimulation (Figure 3C, 3D) and in the livers of mice induced to develop hepatic fibrosis by receiving CCl4 injection (Figure 3E, 3F), TAA injection (Figure 3G, 3H), or undergoing BDL (Figure 3I, 3J), suggesting that HDAC4 levels may potentially serve as a marker for liver fibrogenesis. The gene discussed is TGFB1; the disease is Hepatic fibrosis.