PMAIP1 and neoplasm: Indeed, NOXA was even required for optimal starvation‐induced autophagy of melanoma cells and the authors speculated that a dynamic balance between MCL1/NOXA and MCL1/Beclin‐1 complexes may regulate ‘autophagy or apoptosis’ decisions during nutrient starvation, with ERK‐driven expression of NOXA favouring autophagy to facilitate tumour cell survival under nutrient‐poor conditions 72.