Unlike rLCMV-OVA and rAd-OVA, which showed partial or no clinical benefit, respectively, when administered to mice with an established solid tumour, treatment with artLCMV-OVA afforded substantial tumour control and prolonged the animals' survival in a CD8+ T-cell-dependent manner (Fig. 6a,b, Supplementary Fig. 5a,b). The gene discussed is CD8A; the disease is neoplasm.