EHMT2 and neoplasm: To determine the anti-tumour activity of simultaneous inhibition of G9a and DNMTs methyltransferase activity, we evaluated, by MTS (3-4(,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium) assay, the effect of CM-272 and CM-579 treatment in a collection of 75 cell lines derived from human patients with a wide range of cancers.