2015; Yakirevich et al. 2015) and had histologic features, which were consistent with the histology typically associated with SDHB associated RCC (Ozluk et al. 2015; Yakirevich et al. 2015). One patient with a novel somatic 17 kbp SDHA homozygous deletion on chromosome 5p15, had malignant RCC (Yakirevich et al. 2015). This evidence concerns the gene SDHB and renal cell carcinoma.