However, in hypertrophic scars and keloids, these myofibroblasts persist at a high number for long periods and promote the synthesis of α-smooth muscle actin (α-SMA), transforming growth factor-β1 (TGF-β1), and other growth factors, and they have sustained contractile ability via the TGF-β1 positive loop [6]. Here, TGFB1 is linked to keloid.