Martinez-Outschoorn and colleagues reported that treatment with antioxidants (such as N-acetyl-cysteine, metformin, and quercetin) or NO inhibitors was sufficient to reverse many of the Cav-1 loss-induced phenotypes, such as mitochondrial dysfunction, oxidative stress, and aerobic glycolysis in cancer-associated fibroblasts [60]. Here, CAV1 is linked to cancer.