The PTX3 levels and other indicators of endothelial dysfunction (like the soluble form of E-selectin (sE-selectin), VCAM-1 (sVCAM-1), MCP-1 (monocyte chemotactic protein-1), and von Willebrand factor (vWF)) were estimated in plasma and serum of 56 women with SLE. This evidence concerns the gene PTX3 and systemic lupus erythematosus.