These results are consistent with the expression levels of FGF9 in the hippocampal areas of 24 week-old mice (4 months of treatment), as reported in Fig. 1, panel D. Based on published data indicating that specific growth factor transcripts are altered in depressed, stressed, and AD-affected brains56–58, we selectively examined FGF9 differential expression in AD and wt mice. Here, FGF9 is linked to Alzheimer disease.