In accordance with the literature we found that the best prognostic PET/CT response parameter for both pCR breast and pCR axilla is ∆SUVmax between baseline PET/CT and PET/CT after 6 weeks in TN tumours and the absolute SUVmax value at PET/CT after 3 weeks of therapy in HER2-positive tumours [9, 12, 30, 31, 35]. Here, ERBB2 is linked to neoplasm.