Indeed, TGF-β expression levels were found altered by HPV presence and decreased as cell malignancy progress from cervical intraepithelial neoplasia to carcinoma [72], being suggested that it owns a dual role: it acts as a growth inhibitor in low-grade lesions, but as pro-oncogenic in high-grade and carcinoma lesions [73]. The gene discussed is TGFB1; the disease is carcinoma.