BCL2 and cancer: In vitro, various cancer cells were exposed to F. umbellata aqueous (AE) and methanolic (MeOH) extracts, and the cytotoxicity, mechanism of cell death, cell cycle analysis, anti-migration and anti-invasion potential, reactive oxygen species (ROS) levels, mitochondrial transmembrane potential, caspase activities and Bcl-2 family proteins content were studied.